The disappearance of 84-year-old Nancy Guthrie has grown from a local missing persons case into a national investigation. As of February 2026, Tucson authorities—alongside the FBI—are conducting an intense forensic search, including a recent hours-long examination of the home of Annie Guthrie, sister of Today anchor Savannah Guthrie. Deputies were seen documenting evidence and removing items, though no family members have been named suspects.

Nancy was last seen after a family dinner. Annie’s husband, Tommaso Cioni, reportedly drove her home, making him the last known person to see her. When she missed church the next morning, relatives checked her house and found her wallet and phone left behind, along with troubling blood spatter—signs she likely didn’t leave voluntarily.

The FBI has offered a $50,000 reward. The case intensified after cryptic ransom-style messages were sent to media outlets and the family, prompting an emotional public plea from Savannah, who said they would pay for her mother’s safe return. A reported electronic signal briefly raised hope, but attention shifted after the arrest of Derrick Callella. Authorities have not disclosed the charges or his exact connection to the case.

Despite other headlines competing for attention, the Guthrie investigation stands out for its human stakes. Behind the forensic searches, cryptic notes, and media coverage is a family in anguish. Savannah Guthrie, long a reporter of others’ tragedies, now waits for answers in her own.

The search continues, focused on uncovering the truth and securing justice—or closure—for Nancy Guthrie and the family determined not to give up.